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Saturday, April 27

  1. 12:32 pm
  2. page home edited ... {Interferences.jpg} The dynamic reaction cell (DRC) has the ability to reduce or eliminate m…
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    {Interferences.jpg}
    The dynamic reaction cell (DRC) has the ability to reduce or eliminate many of these interferences. Please refer to the hardware manual and/or read
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    ELAN software.
    Brine Analysis
    High levels of salt may confound the analysis process. Some methods in the literature that may prove useful:
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    Melted ICP Torch
    The ICP torch on the ICP-MS is located within a coiled wire adjacent to the cones (figure). Its proper function is dependent on having adequate exhaust ventilation, which has been known to be periodically non-functional in the soil sciences laboratory. Unfortunately, staff and scientists are not always made aware when these outages occur. If the ventilation system is not working and the ICP-MS is turned on, the very hot plasma torch exhaust will accumulates around the torch, causing the plasma torch to melt almost immediately. Should this happen, the torch will appear visually melted upon inspection, and will have to be replaced. ICP torch maintenance is detailed in section 4-15 of the Hardware Guide.
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    DRC II. {http://www.h-baumbach.co.uk/004.jpg} Examples of destroyed ICP torches (taken from online source).
    References Cited
    1.PerkinElmer Instruments. The 30-Minute Guide to ICP-MS; Electronic Document. www. perkinelmer. com/Catalog/CategoryPage. htm: 2001. http://www.perkinelmer.com/PDFs/Downloads/tch_icpmsthirtyminuteguide.pdf
    (view changes)
    12:29 pm
  3. page home edited ... The software responsible for the operation of the ICP-MS is called the ELAN 3.4 ICP-MS Instrum…
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    The software responsible for the operation of the ICP-MS is called the ELAN 3.4 ICP-MS Instrument Control Software and runs on an attached Windows OS computer. The Software Reference Guide contains detailed information on how to use this software to achieve the best analytical results possible.
    Methods and SOP's
    "Determination of Trace Elements in Waters and Wastes by Inductively Coupled Plasma-Mass Spectrometry" by Long et. al. (1994).
    {Long et al 1994 ICPMS Method.pdf}
    "Interference Removal and Analysis of Environmental Waters Using the ELAN DRC-e ICP-MS" by Neubauer and Wolf (2004).
    The
    The method development
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    soil testing lablab. When you are ready to create your own experiment on the ICP-MS, follow these standard operating procedures (SOPs) to turn the instrument on and ready it before using the software to select or create a method.
    {ICP MS method development.pdf}
    Calibration techniques may be found on page 40 of the "Software Reference Guide." Tuning and Optimization may be found on page 85.
    "Determination of Trace Elements in Waters and Wastes by Inductively Coupled Plasma-Mass Spectrometry" by Long et. al. (1994). This details the EPA method for quantification of trace quantities of the elements Al, Sb, As, Ba, Be, Cd, Cr, Co, Cu, Pb, Mn, Hg, Mo, Ni, Se, Ag, Tl, Th, U, V, and An dissolved in water.
    {Long et al 1994 ICPMS Method.pdf}
    "Interference Removal and Analysis of Environmental Waters Using the ELAN DRC-e ICP-MS" by Neubauer and Wolf (2004). This paper, sponsored by PerkinElmer, lists the ELAN DRC II's known interferences and how to amend your method to avoid false positives.
    Refer to the "Software Reference Guide," page 23, for more specifics on developing your own method.

    Matrix Interferences
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    Ray and Weidmeyer.Weidmeyer and also "Interference Removal and Analysis of Environmental Waters Using the ELAN DRC-e ICP-MS" by Neubauer and Wolf (2004).
    {Interferences.jpg}
    The dynamic reaction cell (DRC) has the ability to reduce or eliminate many of these interferences. Please refer to the hardware manual and/or read
    ...
    et. al. See page 145 of the Software Reference Guide for specific instructions on how to correct interferences with the ELAN software.
    Brine Analysis
    SomeHigh levels of salt may confound the analysis process. Some methods in the literature that
    "Determination of trace metals in sea water by ICP-MS after matrix separation" by Sekhar et. al. (2003).
    "Direct determination of trace elements in sea-water using reaction cell inductively coupled plasma mass spectrometry" by Louie et. al. (2002).
    Troubleshooting and General Maintenance
    {Underhood.jpg} Under the lid of the ELAN DRC II
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    the issue. Whenever a new problem is encountered with the ELAN DRC II, please take pictures of the process and add them here such that others may benefit. This section
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    the Hardware GuideGuide, and the two should be
    Note that any consumables needed for the ELAN DRC II may be bought at PerkinElmer's online catalogue.
    Tubing Problems
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    and breaks. Section 4-30 of the Hardware Guide includes detailed instructions for pump and tube maintenance.
    {Tubes.jpg} Tubing system responsible for analyte delivery to nebulizer.
    Clogged Sampler and Skimmer Cones
    {Dirty cone.jpg} What very, very dirty sampler and skimmer cones looks like.
    {Dirty cone and base.jpg} Notice the salt build-up.
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    instrument again. Section 4-35 and 4-36 of the Hardware Guide detail how to remove, clean, and reinstall the cones and O-rings.
    {Cone cleaning.jpg} Using a cotton swab and 5% nitric acid solution to gently clean the platinum inlet port.
    {Cone soaking.jpg} Soaking the platinum cone tip only in 5% nitric acid solution.
    Melted ICP Torch
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    be replaced. ICP torch maintenance is detailed in section 4-15 of the Hardware Guide.
    {Plasmatorch.jpg} The plasma torch of the ELAN DRC II.
    References Cited
    (view changes)
    12:23 pm

Friday, April 26

  1. page home edited ... The software responsible for the operation of the ICP-MS is called the ELAN 3.4 ICP-MS Instrum…
    ...
    The software responsible for the operation of the ICP-MS is called the ELAN 3.4 ICP-MS Instrument Control Software and runs on an attached Windows OS computer. The Software Reference Guide contains detailed information on how to use this software to achieve the best analytical results possible.
    Methods and SOP's
    ...
    al. (1994). {Long
    {Long
    et al
    "Interference Removal and Analysis of Environmental Waters Using the ELAN DRC-e ICP-MS" by Neubauer and Wolf (2004).
    ...
    testing lab {ICP
    {ICP
    MS method
    Matrix Interferences
    Occasionally, the Ar gas from the ICP will react with other molecules found within the matrix to produce polyatomic species which occur at the exact correct m/z ratio to produce false positive detection of a given analyte. A full list of interferences may be viewed in the document "A Table of Polyatomic Interferences in ICP-MS" by Ray and Weidmeyer.
    (view changes)
    8:08 am
  2. page home edited ... "Determination of Trace Elements in Waters and Wastes by Inductively Coupled Plasma-Mass …
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    "Determination of Trace Elements in Waters and Wastes by Inductively Coupled Plasma-Mass Spectrometry" by Long et. al. (1994). {Long et al 1994 ICPMS Method.pdf}
    "Interference Removal and Analysis of Environmental Waters Using the ELAN DRC-e ICP-MS" by Neubauer and Wolf (2004).
    ...
    soil testing lab.
    {ICP
    lab {ICP MS method
    Matrix Interferences
    Occasionally, the Ar gas from the ICP will react with other molecules found within the matrix to produce polyatomic species which occur at the exact correct m/z ratio to produce false positive detection of a given analyte. A full list of interferences may be viewed in the document "A Table of Polyatomic Interferences in ICP-MS" by Ray and Weidmeyer.
    (view changes)
    8:06 am
  3. page home edited ... Theory and Principles This YouTube video from Agilent Technologies provides a good (albeit ov…
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    Theory and Principles
    This YouTube video from Agilent Technologies provides a good (albeit overdramatic) overview of what occurs inside an ICP-MS instrument. Additionally, the PerkinElmer technical note The 30-Minute Guide to ICP-MS provides an excellent summary of ICP-MS and its capabilities.
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    quadrupole. The quadrupole filtersquadrupolefilters out all
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    performs isotope analysis.analysis (see: "Accurate and precise determination of isotopic ratios by MC-ICP-MS: A review " by Lang, 2009). Because the
    The PerkinElmer ELAN DRC II ICP Mass Spectrometer
    The ICP-MS in discussion here is the ELAN DRC II by PerkinElmerSCIEX Instruments, located in the soil testing lab on the third floor of the Natural and Environmental Sciences building (NESB). Contact the soil testing lab to sign up for use of this instrument. It may be helpful to potential users of this instrument to take one of PerkinElmer's online training courses focusing on its use, applications, and basic maintenance.
    (view changes)
    7:58 am

Thursday, April 25

  1. 11:25 pm
  2. page home edited ... Reaction cells and collision cells for ICP-MS: a tutorial review by Scott D. Tanner et. al. B…
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    Reaction cells and collision cells for ICP-MS: a tutorial review by Scott D. Tanner et. al.
    Brine Analysis
    AnalyzingSome literature that may prove useful:
    "Determination of trace
    metals in very salty water.sea water by ICP-MS after matrix separation" by Sekhar et. al. (2003).
    "Direct determination of trace elements in sea-water using reaction cell inductively coupled plasma mass spectrometry" by Louie et. al. (2002).

    Troubleshooting and General Maintenance
    {Underhood.jpg} Under the lid of the ELAN DRC II
    (view changes)
    11:23 pm
  3. page home edited ... "Determination of Trace Elements in Waters and Wastes by Inductively Coupled Plasma-Mass …
    ...
    "Determination of Trace Elements in Waters and Wastes by Inductively Coupled Plasma-Mass Spectrometry" by Long et. al. (1994). {Long et al 1994 ICPMS Method.pdf}
    "Interference Removal and Analysis of Environmental Waters Using the ELAN DRC-e ICP-MS" by Neubauer and Wolf (2004).
    The method development gude for the ELAN DRC II by the soil testing lab.
    {ICP MS method development.pdf}

    Matrix Interferences
    Occasionally, the Ar gas from the ICP will react with other molecules found within the matrix to produce polyatomic species which occur at the exact correct m/z ratio to produce false positive detection of a given analyte. A full list of interferences may be viewed in the document "A Table of Polyatomic Interferences in ICP-MS" by Ray and Weidmeyer.
    (view changes)
    11:18 pm

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